Peter L. Nagy
Columbia University, USA
Biography
Peter L. Nagy received his MD degree from the University of Pecs, Hungary in 1989. His interest to pursue a career as a physician scientist led him to Purdue University where he earned his Ph.D. in Biochemistry.He worked under the mentorship of Dr. Howard Zalkin and made important discoveries relating to C1-metabilism in bacteria. Subsequently he completed Anatomic and Molecular Genetic Pathology training and Stanford University as well as postdoctoral training in Michael Cleary’s laboratory. He was the first to purify and functionally characterize the Set1 histone methyltransferase complex from S. cerevisiae in collaboration with Dr. Roger Kornberg. He co-developed the FAIRE method with Jason Lieb allowing physical fractionation of chromatin based on formaldehyde crosslinkability. Currently he leads a research laboratory investigating the role of transcriptional defects in neurodegenerative diseases, such as AOA2 and ALS4, and is director of the clinical next-generation sequencing facility in the Laboratory of Personalized Genomic Medicine at Columbia University Medical Center in the Department of Pathology and Cell Biology.