Emmanuel Mic. Drakakis
Imperial College London, UK
Title: Ultra low power cytomimetic VLSI circuits: Synthesis method & proof-of-concept results
Biography
Biography: Emmanuel Mic. Drakakis
Abstract
The physics-dictated sub-threshold operation of MOS transistors can lead to ultra-low-power designs but is also governed by a challenging exponential characteristic. This talk will elucidate how to view such a non-linearity as an asset and how to exploit it by treating it as a powerful computational primitive which can lead to the systematic realisation of non-linear dynamics dictated by biology. We will present a method for the systematic implementation of ultra low power microelectronic circuits aimed at computing nonlinear cellular and molecular dynamics. Several examples of systematic computation of non-linear cellular and molecular dynamics by means of ultra-low-power microelectronic cytomimetic circuits will be elaborated: glycolytic oscillations, nonlinear intracellular calcium oscillations and a gene-protein regulatory system model. Proof-of-concept results from a 1 microwatt cytomimetic prototype chip emulating the complex non-linear mammalian cell cycle dynamics will be reported.